V Wee yong lab calgary
     

Viktor Skihar, MD, PhD

V. Skihar

Education:

  • Medical Doctor (1994, Chernivtsi State Medical Institute, Chernivtsi, Ukraine)
  • General Surgeon (1997, Bucovinian Medical Academy, Chernivtsi, Ukraine)
  • Doctor of Philosophy (2004, Neuroscience, Department of Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK, Canada)

Research interests or projects:

  • 2004 - present: Harnessing beneficial inflammation via production of growth factors by Th2 lymphocytes to promote oligodendrogenesis and remyelination
  • 2004 - present: Axonal injury within a focal cytokine-induced demyelinated lesion in an animal model with experimental allergic encephalomyelitis; axonal protection and regeneration.
  • 2004 - present: Extracellular matrix molecules, neuroinflammation and remyelination.
  • 2004 - present: Remyelination and pregnancy.
  • 1998 - 2004: Migration of olfactory ensheathing cells grafted into the rat spinal cord with experimentally developed demyelinated lesions.
  • 2001 - 2004: Human olfactory mucosa as a source of the olfactory ensheathing cells for future cell treatment of multiple sclerosis and CNS injuries.

Publications:

  • 2007, Gregg C, Shikar V, Larsen P, Mak G, Chojnacki A, Yong VW, Weiss S, White matter plasticity and enhanced remyelination in the maternal CNS, J Neurosci 27:1812-1823, 2007 ( See the Publication )

  • 2004, Boyd, G., SKIHAR, V., Kawaja, M., and Doucette, R. Lac-Z expressing olfactory ensheathing cells do not associate with myelinated axons after implantation into the compressed spinal cord. PNAS. 2004. 101(7): 2162-2166.

  • 2003, Boyd, G., SKIHAR, V., Kawaja, M., and Doucette, R. Olfactory ensheathing cells: historical Perspective and therapeutic potential. Anatomic Rec. 2003, 271B: 49-60.

  • 2002, Mohamed, A.A, Avila, J.G., Schultke, E., Kamencic, H., SKIHAR, V., Obayan, A., and Juurlink, B.H.J. Amelioration of experimental allergic encephalitis (EAE) through phase 2 enzyme induction. Biomedical Sciences Instrumentation, 2002; Vol. 38: 9-13.